|
1 / 1
|
DeCS
|
|
 |
|
Descriptor English:
|
|
Transforming Growth Factor beta
|
|
Descriptor Spanish:
|
|
Factor Transformador de Crecimiento beta
|
|
Descriptor Portuguese:
|
|
Fator Transformador de Crescimento beta
|
|
Synonyms English:
|
|
Bone-Derived Transforming Growth Factor
Platelet Transforming Growth Factor
TGF-beta
|
|
Tree Number:
|
|
D12.644.276.374.687
D12.644.276.960.720
D12.776.467.374.687
D12.776.467.960.720
D23.529.374.687
D23.529.960.720
|
|
Definition English:
|
|
A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1, TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3) have been isolated. The TGF-beta proteins are synthesized as precursor proteins. |
|
History Note English:
|
|
91; was see TRANSFORMING GROWTH FACTORS 1989-90; TGF-BETA was see TRANSFORMING GROWTH FACTORS 1989-90
|
|
Allowable Qualifiers English:
|
|
|
|
Record Number:
|
|
29139
|
|
Unique Identifier:
|
|
D016212
|
Occurrence in VHL:
|
|
|
Similar:
|
|
DeCS SciELO LILACS LIS
|